Ethanol-induced conditioned place preference and aversion differentially alter plasticity in the bed nucleus of stria terminalis
نویسندگان
چکیده
منابع مشابه
Conditioned Place Preference and Aversion
The use of a virtual reality environment (VRE) enables behavioral scientists to create different spatial contexts in which human participants behave freely, while still confined to the laboratory. In this article, VRE was used to study conditioned place preference (CPP) and aversion (CPA). In Experiment 1, half of the participants were asked to visit a house for two minutes with consonant music...
متن کاملEffects of lesions of the bed nucleus of the stria terminalis, lateral hypothalamus, or insular cortex on conditioned taste aversion and conditioned odor aversion.
The effects of permanent forebrain lesions on conditioned taste aversions (CTAs) and conditioned odor aversions (COAs) were examined in 3 experiments. In Experiment 1, lesions of the bed nucleus of the stria terminalis had no influence on CTA or COA acquisition. Although lesions of the lateral hypothalamus induced severe hypodipsia in Experiment 2, they did not prevent the acquisition of CTAs o...
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The bed nucleus of the stria terminalis (BNST), part of the extended amygdala, has been shown to have an important role in anxiety, stress, and drug withdrawal. Recent research hints that the BNST also modulates appetitive motivation, including drug reinforcement and feeding. However, it remains unclear whether increased chow consumption following intra-BNST opioid microinjection is simply the ...
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In children, behavioral inhibition (BI) in response to potential threat predicts the development of anxiety and affective disorders, and primate lesion studies suggest involvement of the orbitofrontal cortex (OFC) in mediating BI. Lesion studies are essential for establishing causality in brain-behavior relationships, but should be interpreted cautiously because the impact of a discrete lesion ...
متن کاملEthanol effects on N-methyl-D-aspartate receptors in the bed nucleus of the stria terminalis.
The extended amygdala is a series of interconnected, embryologically similar series of nuclei in the brain that are thought to play key roles in aspects of alcohol dependence, specifically in stress-induced increases in alcohol-seeking behaviors. Plasticity of excitatory transmission in these and other brain regions is currently an intense area of scrutiny as a mechanism underlying aspects of a...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2019
ISSN: 0893-133X,1740-634X
DOI: 10.1038/s41386-019-0349-0